For many years I have taught a class called Ethics of the Future: Analyzing Science Fiction Films, and my focus has been Star Trek: The Original Series.

Source: https://www.counterpunch.org/2023/05/08/captain-kirk-was-not-a-jerk/

M'Benga and Kirk, at least, must survive because both characters are alive by the time of Star Trek: The Original Series.

Source: https://screenrant.com/star-trek-strange-new-worlds-season-3-bridge-explode/

Roddenberry did not want to use the villains from "The Original Series" — his "TNG" production bible says Klingons and Romulans are verboten.

Source: https://www.slashfilm.com/1364741/gene-roddenberry-star-trek-no-interest-worf/

The character of Christopher Pike (Jeffrey Hunter) was introduced in Star Trek: The Original Series' unaired pilot, "The Cage," and made an appearance in the later two-part episode, "The Menagerie."

Source: https://screenrant.com/strange-new-worlds-pike-great-captain-secret-hope/

The regulatory body in charge of television content moderation across the pond, Britain’s Office of Communications (Ofcom) banned four episodes of The Original Series for nearly 20 years.

Source: https://collider.com/star-trek-the-original-series-banned-episodes/

Though set before The Original Series, there are some deviations.

Source: https://www.cbr.com/strange-new-worlds-prequel-star-trek-tos/